New Manchester United signing Andreas Lindegaard is injured for the match against Fulham.
Anderson is also back in contention after coming through a reserve run-out unscathed.
Rafael's knee problem, picked up against Chelsea on Wednesday, is not as bad as first feared, but he will still be missing this weekend.
Owen Hargreaves (shoulder) and Anders Lindegaard (knee) also miss out, while Darren Fletcher is yet to shake off an illness and remains a doubt.
Damien Duff is struggling with an Achilles problem and may be forced to sit out Fulham's trip to Old Trafford.
Northern Ireland centre-back Aaron Hughes is expected to be involved after showing no ill-effects from a heavy blow to the head against Blackpool last weekend.
Striker Bobby Zamora has recovered from a bout of illness and is expected to figure after netting twice against Blackpool last weekend, but Diomansy Kamara (back) and Philippe Senderos (calf) remain sidelined.